What is your favorite round for Prairie Dogs?

I have been through them all, FMJ, HP and now tend to use some  type of polymer plugged hollow point. 
How about you?

Today's featured Dog Guide is bad River (Draper, SD)

I have been thinking about putting together a "tube gun" as of late.

Not that I NEED it, but damn they are sexy.  Seems like it would be a good match to my custom ARs in the stable.

.22-250?  yes please!